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Complement‐Fixing Platelet Iso‐Antibodies
Author(s) -
Svejgaard A.,
KissmeyerNielsen F.
Publication year - 1970
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1970.tb01424.x
Subject(s) - typing , complement fixation test , complement (music) , platelet , antibody , histocompatibility testing , antigen , biology , immunology , medicine , microbiology and biotechnology , human leukocyte antigen , genetics , phenotype , serology , gene , complementation
Summary. The reliability of the complement (C') fixation technique with platelets in HL‐A typing was studied by parallel platelet and Iymphocytotoxie typings of 1098 Scandinavians. With good typing sera the reproducibilities of the two techniques were equal and higher than 99.7%. The following HL‐A antigens was demonstrated on platelets by means of C'‐fixing (C'F) iso‐antibodies: HL‐A1, 2, 3, 5, 7, 8, 9. Ba*, ILN*, FJH, and BB. The corresponding antibodies were used in the platelet typing of between 20 and 525 unrelated Scandinavians and the results were compared with those obtained by means of Iymphocytotoxic typing. Most of the specificities were detected identically or almost so in the two techniques. Preliminary studies of a new HL‐A specificity, EL, are reported.