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Interrelationship of Erythrocyte Blood Group Substances A, B, and H Studied with Immunofluorescence 1
Author(s) -
Cohen Flossie,
Warezak Wanda,
Zuelzer W. W.
Publication year - 1969
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1969.tb04723.x
Subject(s) - reactivity (psychology) , antigen , immunofluorescence , group a , group b , chemistry , biology , antibody , immunology , medicine , pathology , alternative medicine
Summary. Adult O cells generally showed strong anti‐H reactions; A cells showed an inverse relationship between A and H reactivity; B cells often lacked the expected inverse relationship, showing both weak and strong anti‐H reactions. Newborn O cells usually reacted weakly with anti‐H; A cells generally lacked a reciprocal relationship, and reacted weakly with both anti‐A and anti‐H; B cells reacted strongly with anti‐B and weakly with anti‐H. All this suggests a special property of B that produces strong reactions regardless of the number of antigenic molecules. Seemingly, the high reactivity of the B antigen accounts for the behavioral divergence between erythrocytes and soluble substances. The findings in groups A, 4B, and O support the Watleins and Morgan theory.