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Immunofixation Electrophoresis: A Technique for the Study of Protein Polymorphism 1
Author(s) -
Alper C. A.,
Johnson A. M.
Publication year - 1969
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1969.tb00414.x
Subject(s) - immunofixation , electrophoresis , polymorphism (computer science) , antiserum , gel electrophoresis of proteins , microbiology and biotechnology , biology , computational biology , genetics , chemistry , genotype , polyacrylamide gel electrophoresis , antibody , biochemistry , gene , monoclonal , monoclonal antibody , enzyme
Summary. A technique is described which allows direct visualization of individual proteins in mixtures by specific antiserum after electrophoresis. By minimizing diffusion, it permits rapid, direct, and clear detection of genetic polymorphism and ‘conversion’ of proteins in the complement and coagulation systems.