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Antibody/Latex Erythrocyte Label
Author(s) -
Fimmel P. J.
Publication year - 1969
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1969.tb00385.x
Subject(s) - antibody , population , red cell , labelling , red blood cell , chemistry , immunology , chromatography , microbiology and biotechnology , biology , medicine , biochemistry , environmental health
Summary. A new technique, employing antibody coated latex particles, for the labelling and precise estimation of minor red cell populations is described. The technique is shown to be capable of detecting minor populations diluted to at least 1 in 1,000,000 in the major population. Labelled cells are easily differentiated from unlabelled cells in a blood film and there seems to be no inherent limit to the sensitivity of this technique. Examinations of artificial cell mixtures revealed labelled cells in expected numbers.