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Antinuclear Antibodies in Coombs‐Positive Acquired Hemolytic Anemia 1
Author(s) -
Tan E. M.,
Chaplin H.
Publication year - 1968
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1968.tb01745.x
Subject(s) - anti nuclear antibody , reticulocytosis , coombs test , antibody , medicine , immunology , anemia , autoimmune hemolytic anemia , hemolytic anemia , autoantibody
Summary. The incidence of antinuclear antibodies was determined to be 39% in a group of 26 patients with Coombs positive acquired hemolytic anemia who lacked evidence of collagen disease or primary disturbances of the lymphoreticular system. There was no correlation between antinuclear antibodies and such factors as anemia, reticulocytosis, hypergammaglobulinemia and whether the Coombs reaction was related to pure IgG or to serum complement on the red cells. The significance of the antinuclear antibodies and their relationship to the acquired hemolytic process remain to be elucidated.