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The Anti‐D Content of IgG Preparations for Use in the Prevention of Rh Haemolytic Disease
Author(s) -
HughesJones N. C.,
Stevenson Mary
Publication year - 1968
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1968.tb01732.x
Subject(s) - haemolytic disease , labelling , antibody , immunoglobulin g , immunology , chemistry , medicine , biology , biochemistry , pregnancy , fetus , genetics
Summary. Anti‐D concentrations in IgG preparations for use in the prevention of haemolytic disease of the newborn have been estimated by direct labelling of the IgG with 125 I and by an indirect method using 125 I‐labelled antiglobulin. The concentrations ranged from 50–2000 μg anti‐D/ml for total protein concentrations of 10–16 g/100 ml in the IgG preparations.