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The Effect of External Version on Antenatal Immunization by the Rh Factor
Author(s) -
Vos G. H.
Publication year - 1967
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1967.tb03368.x
Subject(s) - placental circulation , rh blood group system , immunization , in utero , medicine , pregnancy , obstetrics , haemolytic disease , placenta , pediatrics , immunology , fetus , antigen , antibody , biology , genetics
Summary The present study has shown that the routine practise of antenatal manipulations such as external version is associated with a significant increase in the frequency of episodes of Rh immunization not only among Rh negative mothers who were already immunized before the present pregnancy commenced but also among those not previously immunized. The findings would seem to indicate that the disruption of the placental circulation is enhanced by such procedures and the ultimate risk involved in intensifying the haemolytic process ‘in utero’ can therefore not be ignored.