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Delayed Haemolytic Transfusion Reactions Simulating Auto‐Immune Haemolytic Anemia
Author(s) -
Croucher Betty E. E.,
Crookston Marie C.,
Crookston J. H.
Publication year - 1967
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1111/j.1423-0410.1967.tb03355.x
Subject(s) - antibody , transfusion reaction , medicine , blood transfusion , anemia , immunology , immune system , antigen , isoantibodies , hemoglobin , haemolytic disease , biology , pregnancy , fetus , genetics
Summary Seven cases, in which the presence of a blood group iso‐antibody was unsuspected until several days after transfusion, are described. In one case the rapid appearance of multiple antibodies produced signs and symptoms simulating auto‐immune haemolytic anaemia. In two of the seven cases, antibodies were detectable in the pre‐transfusion serum only when cells containing a double dose of the corresponding antigen were used.