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Regional cerebral oxygenation by NIRS does not correlate with central or jugular venous oxygen saturation during interventional catheterisation in children
Author(s) -
KNIRSCH W.,
STUTZ K.,
KRETSCHMAR O.,
TOMASKE M.,
BALMER C.,
SCHMITZ A.,
BERGER F.,
BAUERSFELD U.,
WEISS M.
Publication year - 2008
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.2008.01703.x
Subject(s) - medicine , anesthesia , limits of agreement , cardiology , nuclear medicine
Purpose: To evaluate whether regional cerebral oxygenation (rSO 2 ) by near‐infrared spectroscopy correlates with central venous (SvO 2 ) or internal jugular (SjO 2 ) oxygen saturation, and whether changes over time (Δ) in rSO 2 (ΔrSO 2 ) predict changes in SvO 2 (ΔSvO 2 ) and SjO 2 (ΔSjO 2 ). Methods: The rSO 2 values were measured using the INVOS 5100 cerebral oximeter in children undergoing interventional cardiac catheterization and were compared with the oxygen saturation of analysed central venous and internal jugular blood samples. Changes over time (Δ) were calculated as the difference between the values before and after catheter intervention for rSO 2 ·(ΔrSO 2 ), SvO 2 ·(ΔSvO 2 ) and SjO 2 ·(ΔSjO 2 ). Simple regression and Bland–Altman analysis were performed. Data are presented as median (range). Results: Sixty patients aged 4.3 (0.2–16.0) years were investigated. A closer correlation was found between rSO 2 and SvO 2 ( r =0.728, P <0.0001) than between rSO 2 and SjO 2 ( r =0.665, P <0.0001). The bias between rSO 2 and SvO 2 ·(SjO 2 ) was 0.17% (−0.60%), with limits of agreement from −15.5% to 15. 9% (−18.6–17.4%). The sensitivity/specificity for ΔrSO 2 to indicate a fall in SvO 2 or in SjO 2 was 70.3%/65.2% and 68.6%/60.0%, respectively. Conclusion: Neither absolute values nor changes in rSO 2 using the INVOS 5100 allowed reliable estimation of SvO 2 or SjO 2 and their trends.