Premium
Desflurane vs. sevoflurane as the main inhaled anaesthetic for spontaneous breathing via a laryngeal mask for varicose vein day surgery: a prospective randomized study
Author(s) -
Saros G. B.,
Doolke A.,
Anderson R. E.,
Jakobsson J. G.
Publication year - 2006
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.2006.001022.x
Subject(s) - medicine , desflurane , anesthesia , sevoflurane , general anaesthetic , randomized controlled trial , varicose veins , ophthalmic surgery , elective surgery , inhalation , propofol , laryngeal mask airway , general anaesthesia , surgery , airway
Background: Sevoflurane has become widely used in day surgery; however, desflurane may be a valuable alternative even in this setting. This study compares emergence from anaesthesia for day surgery with spontaneous breathing using either desflurane or sevoflurane. Methods: This prospective, randomized, single‐blinded study examined 70 ASA III patients undergoing elective ambulatory varicose vein surgery. Primary endpoint was emergence time (cessation of anaesthetic gas to communicating). Secondary endpoints included post‐operative pain, nausea, time to discharge, and patient satisfaction. Patients were anaesthetized according to a standardized protocol including multimodal analgesia and antiemetic therapy and were randomized to receive sevoflurane or desflurane as the main anaesthetic while breathing spontaneously through a laryngeal mask airway. Fresh gas flow was oxygen in air 1 : 2 l/min. Results: Intra‐operative anaesthesia was uneventful apart from airway irritation observed in 5/35 desflurane and 1/35 sevoflurane patients. Emergence was 25–40% faster in patients anaesthetized with desflurane. Pain and post‐operative nausea and vomiting (PONV) were equally infrequent in both groups. Overall, patient satisfaction was high with no difference between the groups. Conclusion: Desflurane is associated with a faster emergence with no differences during the post‐operative course except a somewhat higher incidence of airway irritation.