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Intensive care unit stay is prolonged in chronic alcoholic men following tumor resection of the upper digestive tract
Author(s) -
Spies C. D.,
Nordmann A.,
Brummer G.,
Marks C.,
Conrad C.,
Berger G.,
Runkel N.,
Neumann T.,
Müller C.,
Rommelspacher H.,
Specht M.,
Hannemann L.,
Striebel H. W.,
Schaffartzik W.
Publication year - 1996
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1996.tb04505.x
Subject(s) - medicine , digestive tract , intensive care unit , resection , chronic alcoholic , surgery , intensive care medicine
Background: The prevalence of chronic alcohol misuse in patients with oral, pharyngeal, laryngeal or esophageal carcinomas exceeds 60%. No data is available, to our knowledge, on the morbidity and mortality of chronic alcoholics in surgical intensive care units (ICU) following tumor resection. We investigated whether the subsequent ICU stay in chronic alcoholics following tumor resection was prolonged and whether the incidence of pneumonia and sepsis was increased. Methods: 213 patients with carcinomas of the upper digestive tract were evaluated regarding their drinking habits. Chronic alcoholics met either the DSM‐III‐R criteria for alcohol abuse or dependence. Conventional laboratory markers and serum carbohydrate‐deficient transferrin were determined preoperatively. Major intercurrent complications during ICU stay such as an alcohol withdrawal syndrome, pneumonia and sepsis as well as the frequency of death were documented. Results: Patients did not differ significantly between groups regarding age or APACHE score on admission to the ICU. 121 patients were diagnosed as being chronic alcoholics, 39 as being social drinkers and 61 as being non‐alcoholics. In chronic alcoholics the frequency of death was significantly increased. Due to the increased incidence of pneumonia and sepsis the ICU stay was significantly prolonged in chronic alcoholics by approximately 8 days. Conclusions: The increased mortality and morbidity rate demonstrates that chronic alcoholics undergoing major tumor surgery have to be considered as high‐risk patients during their postoperative ICU stay. Further studies are required with respect to the immuno‐competence of chronic alcoholics and the prevention of alcohol withdrawal syndrome, pneumonia and sepsis in these patients.