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Gangrene and renal failure caused by dihydroergotamine used to treat raised intracranial pressure following head trauma
Author(s) -
Gupta V. L.,
Mjørndal T. O.
Publication year - 1996
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1996.tb04453.x
Subject(s) - medicine , dihydroergotamine , gangrene , anesthesia , vasospasm , intracranial pressure , thrombosis , venous thrombosis , head trauma , head injury , pain medicine , surgery , intensive care medicine , subarachnoid hemorrhage , anesthesiology , migraine
A case of peripheral gangrene and renal failure following the use of dihydroergotamine (DHE) for treatment of raised intracranial pressure (ICP) is reported. There have been several reports of vasospasm and peripheral gangrene caused by DHE used in combination with heparin for prevention of deep venous thrombosis. Clinical experience with the use of DHE in head trauma is limited. This case report emphasises the seriousness of the adverse effects associated with the use of this drug.