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A maximal central venous oxygen saturation (SvO 2 max) for the surgical patient
Author(s) -
JENSTRUP M.,
EJLERSEN E.,
MOGENSEN T.,
SECHER N. H.
Publication year - 1995
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1995.tb04326.x
Subject(s) - medicine , anesthesia , saline , isotonic , central venous catheter , isotonic saline , oxygen saturation , intravascular volume status , catheter , oxygen , surgery , hemodynamics , chemistry , organic chemistry
Before induction of anaesthesia, 23 patients scheduled for major abdominal surgery had blood samples drawn from a central venous catheter for oxygen saturation (SvO 2 ) after graded infusion of isotonic saline. The infusion of saline was continued until further administration resulted in a stable SvO 2 (SvO 2 max). The SvO 2 increased from 69 (53–83) to 72 (66–83) % (median and range; P < 0. 0001), when the patients received 10 (0–26) mL‐ kg ‐1 , average 500 mL, of saline. At the same time central venous haematocrit decreased from 38 (32–47) to 36 (23–47) % which suggests that the intravascular volume was expanded by 420 (180–3070) mL or by 72 (18–174) % of the administered volume. The results demonstrate that volume expansion by saline can establish a maximal venous oxygen saturation in the surgical patient.