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Intradermal anaesthesia: comparison of several compounds
Author(s) -
PRIEN TH.
Publication year - 1994
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1994.tb04008.x
Subject(s) - medicine , visual analogue scale , anesthesia , mepivacaine , analgesic , procaine , cannula , saline , potency , pain score , surgery , local anesthetic , biochemistry , chemistry , in vitro
Objective: To compare the efficacy of different local anaesthetics to produce intradermal anaesthesia for venous cannulation and the discomfort associated with skin infiltration. Measurements: A visual analog scale (VAS) for pain (0 = no pain/10 = most pain imaginable) was used to assess pain elicited by raising the skin wheal and inserting the cannula. Main results: With regard to analgesic potency all five local anaesthetics were comparable (mean VAS–score 1.7–2.09) and effective when compared to 0.9% saline (mean VAS–score 4.2; P < 0.001). Infiltration pain was least with mepivacaine–1 (mean VAS–score 1.0; P < 0.001) and highest with procaine (mean VAS score 2.7; P < 0.001).