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Measurement of dead–space in a model lung using an oscillating inspired argon signal
Author(s) -
WILLIAMS E. M.,
GAVAGHAN D. J.,
OAKLEY P. A.,
SAINSBURY M. C.,
XIONG L.,
BLACK A. M. S.,
HAHN C. E. W.
Publication year - 1994
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1994.tb03853.x
Subject(s) - dead space , medicine , sinusoid , amplitude , signal (programming language) , breathing , forcing (mathematics) , argon , space (punctuation) , mechanics , physics , anesthesia , optics , respiratory system , atomic physics , atmospheric sciences , linguistics , philosophy , pathology , computer science , programming language
In a model lung, airways dead–space can be accurately measured using a forced inspired oscillating argon signal, which varies sinusoidally about a mean concentration of 6% v/v with an amplitude of ± 4% v/v. With sinusoid forcing periods longer than 120 seconds, and at a breathing rate of 13.4 breaths minute ‐1 , the mean airways dead–space can be measured with a standard error of less than 5%. Sinusoid forcing periods shorter than 120 s provided inaccurate estimates of dead–space and so should not be used with this technique.