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Enhanced pneumonia resolution by inhalation of nitric oxide?
Author(s) -
Blomqvist H.,
Wickerts C. J.,
Andreen M.,
Ullberg U.,
ÖOUrtqvist ÅAR.,
Frostell C.
Publication year - 1993
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1993.tb03610.x
Subject(s) - medicine , nitric oxide , inhalation , pneumonia , hypoxic pulmonary vasoconstriction , anesthesia , airway , vasoconstriction
We present a patient with severe bacteraemic pneumococcal pneumonia associated with severe hypoxaemia, where nitric oxide (NO) 15–40 ppm was added to the inspired gas. Nitric oxide therapy improved gas exchange, reduced pulmonary vasoconstriction and peak airway pressure. The patient survived. We observed an unexpected rapid and complete disappearance of bilateral pulmonary infiltrates during the first 120 h of the 7‐day NO inhalation period.