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Postoperative decline in plasma aspirin‐esterase and cholinesterase activity in surgical patients
Author(s) -
Puche E.,
GÓoAmezValverde E.,
Morillas M. GarcÍiAa,
Jorde F.,
Fajardo F.,
Gil J. M. GarcÍiAa
Publication year - 1993
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1993.tb03590.x
Subject(s) - cholinesterase , medicine , aspirin , anesthesia , basal (medicine) , esterase , plasma concentration , plasma levels , surgical stress , pharmacology , enzyme , biochemistry , biology , insulin
We studied preoperative and postoperative plasma hydrolysis of aspirin and plasma cholinesterase activity in surgical patients. Postoperative aspirin esterase and cholinesterase activities fell sharply (119 ± 32 μg ml h ‐1 and 3746 ± 1068 U I ‐1 respectively; P <0.01) in comparison to basal preoperative values (157 ± 33 μg ml h ‐1 and 4620 ± 940 U I ‐1 respectively, P ± 0.01). We suggest that alterations in plasma esterase during the postoperative period may be related to the metabolic response to anesthesia‐ and surgery‐induced stress.