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Volume substitution in shock
Author(s) -
Haljamäe H.
Publication year - 1993
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1991.tb05069.x
Subject(s) - medicine , shock (circulatory) , coagulation , blood volume , dextran , plasma volume , anesthesia , platelet , regimen , colloid , blood flow , surgery , biochemistry , chemistry
Shock treatment seems optimal when a “balanced” fluid and volume regimen, including both crystalloid (Ringer's acetate) and about 3% colloid, is used. Dextran is the colloid of choice due to its beneficial effects on plasma volume, hemorrheology, and microvascular blood flow. Dextrans exert, in addition, inhibiting effects on the shock‐ and trauma‐induced activation of the cascade system, whereby the risk of complications in the form of multiple organ failure is reduced. Infusion of red blood cells, plasma or thrombocytes should be based on a proper assessment of each individual patient's actual need of oxygen transporters and coagulation factors.