Premium
Effects of pleural fluid and positive end‐expiratory pressure on the measurement of extravascular lung water by the double‐indicator dilution technique
Author(s) -
Blomqvist H.,
Wickerts C.J.,
RÖoUsblad P.G.
Publication year - 1991
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1991.tb03352.x
Subject(s) - medicine , positive end expiratory pressure , indicator dilution , dilution , lung , anesthesia , saline , ventilation (architecture) , cardiac output , mechanical ventilation , hemodynamics , mechanical engineering , physics , engineering , thermodynamics
The reliability of the double‐indicator dilution technique (dye/cold) for measuring extravascular lung water (EVLW) has been studied in lung‐healthy dogs after pleural fluid injection of saline (up to 20 ml/kg) during mechanical ventilation at zero and 10 cmH 2 O (1.0 kPa) end‐expiratory pressure (ZEEP and PEEP, respectively). Pleural fluid injection had no effect on EVLW at either ZEEP or PEEP. PEEP induced changes in cardiac output, and reduced both the intravascular (dye) and the thermal indicator volumes, but with no effect on the calculated EVLW. It is concluded that pleural fluid up to 20 ml/kg and ventilation with PEEP of 10 cmH 2 O (1.0 kPa) do not affect the reliability of the double‐indicator dilution technique for measuring extravascular lung water in the dog.