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The effect on uteroplacental blood flow of epidural anaesthesia containing adrenaline for caesarean section
Author(s) -
Skjöldebrand A.,
Eklund J.,
Lunell NO.,
Nylund L.,
Sarby B.,
Thornström S.
Publication year - 1990
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1990.tb03048.x
Subject(s) - medicine , caesarean section , anesthesia , blood flow , bupivacaine , blood pressure , pregnancy , genetics , biology
The effect on uteroplacental blood flow of an epidural anaesthesia containing adrenaline for caesarean section was investigated in ten healthy women using dynamic placental scintigraphy with indium‐113m and a computer‐linked gamma camera. The epidural anaesthesia was performed with 18–22 ml bupivacaine 5mg/ml with adrenaline 2.5 μg/ml followed by an i.v. balanced electrolyte infusion of 10 ml/kg b.w. A significant median decrease in the total maternal placental blood flow of 34% was found ( P <0.01). There was also a significant decrease in maternal mean blood pressure of 3 mmHg (0.4 kPa) ( P <0.05) and a significant negative correlation between the change in maternal blood pressure and the change in uteroplacental blood flow (r= –0.69, P <0.05).