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Analgesia for appendectomy: comparison of fentanyl and alfentanil in children
Author(s) -
Sfez M.,
Mapihan Y. Le,
Gaillard J. L.,
Rosemblatt J. M.
Publication year - 1990
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1990.tb03036.x
Subject(s) - medicine , alfentanil , fentanyl , anesthesia
During etomidate‐N 2 O vecuronium anaesthesia for appendectomy, three groups of 13 children received fentanyl as a 10 μg · kg ‐1 loading dose and 2 μg · kg ‐1 increments in Group F, alfentanil as a 100 μg · kg ‐1 initial loading dose and either 20 μg · kg ‐1 increments in Group AB or 1 μg · kg ‐1 · min ‐1 continuous infusion in Group AI. On the basis of intraoperative heart rate changes, the opioid regimen was less efficient in Group AB ( P < 0.05). Based upon equianalgesic cumulative dosage, the alfentanil/fentanyl potency ratio was in the range of 1/10 to 1/13. The awakening time was similar in all groups, as were the duration of postoperative analgesia, the incidence of postoperative pain and the incidence of nausea and vomiting. We conclude that high‐dose alfentanil is as efficient as fentanyl for intra and postoperative analgesia in children undergoing appendectomy.