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Hemodilution ‐ possibilities and safety aspects
Author(s) -
Messmer Konrad
Publication year - 1988
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1988.tb02843.x
Subject(s) - medicine , hematocrit , cardiac output , anesthesia , blood volume , stroke volume , blood flow , intensive care medicine , hemodynamics , cardiology , blood pressure , heart rate
Normovolemic hemodilution is an essential part of the overall strategy to avoid exposure of patients to the hazards of homologous blood transfusions. It includes beneficial effects on the flow properties and flow conditions of blood. A hematocrit of 30% can be regarded as an optimal compromise between the fluidity and the oxygen content of the blood. Compensatory responses such as increased cardiac output and stroke volume occur following hemodilution. In patients with compromised coronary reserve the degree of hemodilution that is tolerated has to be carefully considered. Therefore specific selection criteria for patients to be preoperatively hemodiluted are needed. For reasons of safety, efficiency and practicability colloid solutions rather than crystalloid solutions should be used for intentional hemodilution.