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Thoracic and abdominal lymph drainage in relation to mechanical ventilation and PEEP
Author(s) -
Frostell C.,
Blomqvist H.,
Hedenstierna G.,
Halbig I.,
Pieper R.
Publication year - 1987
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1987.tb02592.x
Subject(s) - medicine , lymph , positive end expiratory pressure , ventilation (architecture) , mechanical ventilation , lung , anesthesia , pathology , mechanical engineering , engineering
Thoracic and abdominal lymph flow have been studied in 25 dogs. Thoracic lymph flow (TLF) was found to be (mean ± s.e. mean) 6.1 ± 1.4 ml/h before, and 29 ± 4.6 ml/h after the induction of lung damage with oleic acid. TLF was depressed by 50% both before and after lung damage, when a positive end‐expiratory pressure (PEEP) of 1.0 kPa (10 cmH 2 O) was applied. This suggests impeded drainage of the lung tissue. Spontaneous breathing, compared to mechanical ventilation, significantly increased TLF by approximately 70%. Abdominal lymph flow increased from 61 ± 5.3 ml/h to 111 ± 12.6 ml/h, when a PEEP of 1.0 kPa was applied. These findings demonstrate that PEEP may contribute to oedema in a surgical area. It is concluded that increased intrathoracic pressure reduces TLF, and spontaneous breathing increases TLF, as compared to mechanical ventilation without PEEP.