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Thermoregulation, plasma catecholamine and metabolite levels during submaximal work in individuals susceptible to malignant hyperpyrexia
Author(s) -
Green J. H.,
Ellis F. R.,
Halsall P. J.,
Campbell I. T.,
Currie S.,
Caddy J.
Publication year - 1987
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1987.tb02533.x
Subject(s) - medicine , thermoregulation , catecholamine , metabolite , endocrinology , physiology
Measurements of body temperature, respiratory gas exchange, sweat evaporation rate and circulating level of catecholamines, lactate, pyruvate, free fatty acids and glucose were made in seven patients susceptible to malignant hyperpyrexia (MHS) and in seven control subjects during 2 h of treadmill walking at 40% of maximum oxygen consumption. These studies took place in an ambient temperature or 22°C. The MHS patients displayed the same thermoregulatory, plasma catecholamine and metabolic responses as the control subjects. The results or the present study suggest that non‐competitive. low‐intensity, steady‐state exercise need not be contraindicated for MHS patients.