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CO 2 production after suxamethonium and diazepam
Author(s) -
SchouOlesen A.,
Christensen K. J. S.,
HartmannAndersen F.,
Jørgensen S.
Publication year - 1986
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1986.tb02502.x
Subject(s) - diazepam , medicine , fasciculation , anesthesia , muscle relaxation
The CO 2 ‐production and degree of relaxation after increasing doses of suxamethonium were measured in seven patients undergoing alloplastic surgery of the hip. The study indicates that the CO 2 ‐production rises following the injection of increasing doses of suxamethonium. Another group of patients received diazepam 0.1 mg kg ‐1 before the injection of suxamethonium 1 mg kg ‐1 . CO 2 ‐production was significantly reduced compared to CO 2 production when suxamethonium was not preceded by diazepam. It is suggested that diazepam in doses larger than 0.1 mg kg ‐1 might be effective in preventing fasciculations and postoperative muscle pains before the injection of suxamethonium in a dose of 0.5 mg kg ‐1 .