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Hemodynamic effects of atracurium, vecuronium and pancuronium during sufentanil anesthesia for coronary artery bypass
Author(s) -
Waldmann C. S.,
Wark K. J.,
Sebel P. S.,
Feneck R. O.
Publication year - 1986
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1986.tb02429.x
Subject(s) - sufentanil , medicine , anesthesia , hemodynamics , artery , pancuronium bromide , fentanyl , coronary artery bypass surgery , muscle relaxation , cardiology
A study was undertaken to evaluate the cardiovascular effects of sufentanil, in combination with three different muscle relaxants, used as sole anesthetic with 100% O 2 in 30 patients undergoing elective coronary artery vein graft surgery. Patients were randomly allocated to receive pancuronium (P), vecuronium [V) or atracurium (A) for muscle relaxation. All patients received 15 μg/kg sufentanil at induction followed by 5–10 μg/kg sufentanil prior to sternotomy. At the 95% level of significance no statistical difference was found for any of the measured and derived cardiovascular parameters between groups P, V and A, except for a decreased systolic blood pressure in the atracurium group after induction. Sufentanil in combination with pancuronium or vecuronium provided stable hemodynamic conditions throughout anesthesia. Atrarurium was less satisfactory. We conclude that there is no advantage to be gained, in the presence of beta blockade, from the use of the new generation muscle relaxants as compared to pancuronium during high‐dose sufentanil anesthesia for coronary artery vein grafting.