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Haemodynamic Stability during Anaesthesia Induction and Sternotomy in Patients with Ischaemic Heart Disease
Author(s) -
MILOCCO I.,
LÖF B. AXSON,
WILLIAMOLSSON G.,
APPELGREN L. K.
Publication year - 1985
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1985.tb02235.x
Subject(s) - medicine , droperidol , anesthesia , fentanyl , hemodynamics , intubation , general anaesthesia , tracheal intubation , halothane
A comparison of haemodynamic stability with respect to arterial pressure, heart rate and cardiac output between six commonly used anaesthetic techniques: fentanyl (FE), halothane (HAL), morphine (MO), fentanyl/droperidol (NLA), and thiopentone (two dose levels: PE 3 and PE 6), all supplemented with nitrous oxide, was performed during induction of anaesthesia and sternotomy in 47 patients with good left ventricular function and maintained β‐blockers undergoing coronary bypass surgery. Interventions were kept to a minimum in order to characterize each anaesthesia group. Statistically, the material fell into two parts. The MO, PE 3 and PE 6 groups showed good stability under steady‐state anaesthesia, but variable and often extensive hyperdynamic responses were seen to endotracheal intubation and surgical stimulation. The FE, HAL and NLA groups were characterized by a good stability during the induction‐intubation phase but were unstable when combined with nitrous oxide in the absence of noxious stimuli.