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Effects of Suxamethonium on CO 2 ‐Production
Author(s) -
CHRISTENSEN K. J. S.,
OLESEN A. S.,
JØRGENSEN S.
Publication year - 1985
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1985.tb02228.x
Subject(s) - medicine , anesthesia , intubation , endotracheal intubation , halothane , surgery
Eighteen patients undergoing alloplastic surgery of the hip were divided into three groups, each consisting of six patients. All operations were performed under endotracheal intubation using halothane N 2 O‐O 2 anaesthesia. After a steady state as to CO 2 ‐production had been obtained, suxamethonium 1 mg kg ‐1 was given intravenously to the patients in Group I. A maximum rise in CO 2 ‐production of 14.8% (range: 12.9–16.8) was observed after 5 min. In Group II, patients were pretreated with pancuronium 0.01 mg kg ‐1 : no increase in CO 2 ‐production was observed. The third group received a continuous infusion of suxamethonium. In this group there was an increase in CO 2 ‐production of 17.6% (range: 6.7–22.0) 5 min after start of infusion. The CO 2 ‐production then fell to the preinfusion level over the next 10 min.