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Continuous Positive Airway Pressure Increases Vagal and Phrenic Nerve Activity in Cats
Author(s) -
NORSTED T.,
JONZON A.,
SEDIN G.
Publication year - 1985
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1985.tb02227.x
Subject(s) - medicine , vagus nerve , phrenic nerve , anesthesia , expiration , vagotomy , continuous positive airway pressure , chloralose , efferent , superior laryngeal nerve , cats , diaphragmatic breathing , respiratory system , anatomy , larynx , stimulation , afferent , obstructive sleep apnea , alternative medicine , pathology
To investigate how continuous positive airway pressure (CPAP) changes the vagal nerve activity and whether CPAP alters the efferent phrenic nerve activity or the breathing pattern similarly before and after vagotomy, a study was made of vagal and phrenic nerve activity in chloralose‐anaesthetized cats. In the vagal nerve , CPAP increased the mean impulse frequency during expiratory rest. The breath‐related impulse frequency also increased with CPAP. With higher CPAP (≥ 0.5 kPa), the peak of breath‐induced activity in the vagal nerve lasted longer than inspiration. In the phrenic nerve , the impulse frequency in the bursts increased almost linearly with CPAP irrespective of whether the vagal nerves were intact or not. The duration of the phrenic nerve bursts decreased with increasing CPAP when the vagal nerves were intact. When the vagal nerves were cut, the burst duration did not change. The rate of breathing was almost unchanged by CPAP regardless of whether the vagal nerves were cut or not. The inspiration/expiration ratio decreased with increasing CPAP when the vagal nerves were intact, but not when they were cut.