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Vecuronium and Atracurium in the Elderly: A Clinical Comparison with Pancuronium
Author(s) -
LOWRY K. G.,
MIRAKHUR R. K.,
LAVERY G. G.,
CLARKE R. S. J.
Publication year - 1985
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1985.tb02224.x
Subject(s) - medicine , anesthesia , atracurium besilate , block (permutation group theory) , neuromuscular blockade , geometry , mathematics
The intubating conditions, time to complete block and duration of clinical relaxation were observed in a group of 101 elderly patients (aged over 65 years) following pancuronium 0.1 mg kg ‐1 , vecuronium 0.1 mg kg ‐1 or atracurium 0.5 mg kg ‐1 . The intubating conditions in the three groups were similar when assessed at 2 min following relaxant administration. The time to complete block was shortest with vecuronium (4.3 min) in comparison to atracurium (5.0 min) and pancuronium (6.0 min), but the differences were not statistically significant. The duration of clinical relaxation, however, was significantly shorter with vecuronium (37 min) and atracurium (35 min) in comparison to pancuronium (99 min).