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The Effect of High‐Dose Fentanyl Anaesthesia on P 50 in Man
Author(s) -
Damen J.,
Sprokholt R.,
Sinclair D.,
Maas A.
Publication year - 1985
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1985.tb02194.x
Subject(s) - medicine , fentanyl , anesthesia , muscle relaxation , general anaesthesia
The effect of high dosage fentanyl anaesthesia on P 50 was studied in patients undergoing coronary bypass surgery. After induction of fentanyl anaesthesia 100 μg.kg ‐1 with pancuronium muscle relaxation P 50 changed significantly ( P <0.005) from 3.40 ± 0.12 ± 3.33 ± 0.13 kPa. This anaesthesia technique decreases P 50 in vivo , but this has more theoretical than practical importance.