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Metabolic Correlates in Infants and Children During Anaesthesia and Surgery
Author(s) -
LindahiM.D. S. G. E.,
Hulse M. G.,
Hatch D. J.
Publication year - 1984
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1984.tb02010.x
Subject(s) - medicine , respiratory quotient , ventilation (architecture) , anesthesia , capnography , respiratory minute volume , halothane , carbon dioxide , zoology , respiratory system , mechanical engineering , ecology , engineering , biology
In 58 infants and children with body weights between 2.8 and 20.5 kg carbon dioxide production (V. co 2 ml min ‐1 ) was measured during halothane anaesthesia for minor surgical procedures. In 22 cases measurements were made during both spontaneous and controlled ventilation during the same operation. A non‐rebreathing circuit was used. Expired ventilation volume was measured with a dry gas meter and expired gas collected during 3–5 min in a Douglas bag. The carbon dioxide fraction of exhaled gas was determined with a sampling Gould capnograph. A respiratory quotient (RQ) of 0.8 was used to calculate oxygen consumption (V. o 2 ml min 1 ). During spontaneous breathing, regression analysis of the relationship between V. co 2 and kg and between V. o 2 and kg showed high intercepts while corresponding relations to kg revealed an almost direct proportionality. Thus, V. co 2 and V. o 2 ought to be related to body weight in kg in spontaneously breathing children. The mean value (±1 s.d.)for V.co 2 was 11.4 ±3.1 ml kg ‐3/4 and for V. o 2 14.2 ±3.9 ml kg ‐3/4 . During controlled ventilation, the relationship between kg b. w. showed for V. co 2 as well as for V. o 2 an almost direct proportionality with a mean value (± 1 s.d.) for V.co 2 of 6.3± 1.6 ml min 1 kg ‐1 and for V. o 2 of 7.8±2.0 ml min kg. Prediction of V. o 2 for infants and children of this size could be based upon 14Xkg during halothane anaesthesia and surgery.