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Attenuation of the Circulatory Response to Laryngoscopy and Intubation by Fentanyl
Author(s) -
Kautto U.M.
Publication year - 1982
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1982.tb01757.x
Subject(s) - fentanyl , medicine , laryngoscopy , anesthesia , intubation , heart rate , tracheal intubation , blood pressure , saline , mean arterial pressure , circulatory system , cardiology
The effects of fentanyl on arterial pressure and heart rate increases during laryngoscopy and intubation were studied in 45 normotensive, surgical patients, who were randomly allocated to three groups receiving 2 or 6 μg/kg of fentanyl or saline in a double‐blind fashion before anaesthetic induction with thiopental. Fentanyl supplementation with 2 μg/kg significantly attenuated the arterial pressure and heart rate increases during laryngoscopy and intubation, and fentanyl, 6 μg/kg, completely abolished these responses. Moreover, fentanyl given during the induction decreased the amount of fentanyl needed during the operation. Respiratory depression was not observed during recovery.