Premium
Effects of Thiopentone on the Canine Coronary Circulation in Acute Experimental Myocardial Ischaemia
Author(s) -
Smith G.,
Thorburn J. T.,
Rogers K.
Publication year - 1982
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1982.tb01738.x
Subject(s) - medicine , cardiology , circumflex , artery , ischemia , ligation , myocardial ischemia , myocardial ischaemia , blood pressure , anesthesia , coronary circulation , blood flow
Acute myocardial ischaemia was induced in five greyhounds by ligation of the anterior descending branch of the left main coronary artery. Changes in oxygen availability and consumption in the ischaemic area in response to thiopentone 10 mg kg ‐1 were compared with corresponding changes in non‐ischaemic myocardium supplied by the circumflex artery. Despite a 40% reduction in arterial pressure, there were no significant changes in the oxygen availability/consumption ratio in either normal or ischaemic areas.