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Influence of Abdominal Surgical Trauma on Substrate Utilization by the Human Brain
Author(s) -
Stjernstrom H.,
Jorfeldt L.,
Wiklund L.
Publication year - 1981
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1981.tb01641.x
Subject(s) - medicine , jugular vein , oxygen , venous blood , apparent oxygen utilisation , glycerol , internal jugular vein , anesthesia , cholecystectomy , vein , surgery , biochemistry , organic chemistry , chemistry
In 10 patients undergoing cholecystectomy, measurements of jugular venous blood flow (one side) and arterio‐jugular vein differences of oxygen, glucose, lactate, pyruvate, glycerol, 3‐hydroxybutyrate and alanine were made. The arterial concentration of 3‐hydroxybutyrate was raised during surgery, but this substrate only covered a minute part of the total energy demand. The need for substrates of oxidative metabolism in the brain was met by glucose. During the operation the stoichiometrically calculated oxygen uptake was lower than that of glucose, indicating an increase in the brain glucose content.