Premium
Intradermal Histamine Releasing Effect Caused by Org‐NC 45 A Comparison with Pancuronium, Metocurine and d‐Tubocurarine
Author(s) -
Boorj L. H. D. J.,
Erieg N.,
Crul J. F.
Publication year - 1980
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1980.tb01568.x
Subject(s) - medicine , d tubocurarine , pancuronium bromide , histamine , anesthesia , pharmacology
Hiatamine release caused by Org‐NC 45 , pancuronium, metocurine and d‐tubocurarine was determined by measuring the diameter of the redness and skin induration following the intradermal injection of these drugs. d‐Tubocurarine and metocurine caused the largest diameter of redness and induration, followed by pancuronium. Org‐NC 45 caused the smallest reaction. We conclude that Org‐NC 45 may be the drug of choice in patients with asthma and allergic reactions.