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Renal Fluoride Excretion During and After Enflurane Anaesthesia: Dependency on Spontaneous Urinary pH‐Variations
Author(s) -
Järnberg P. O.,
Ekstrand J.,
Irestedt L.,
Santesson J.
Publication year - 1980
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1980.tb01520.x
Subject(s) - enflurane , medicine , fluoride , anesthesia , excretion , urinary system , renal function , general anaesthesia , halothane , urology , inorganic chemistry , chemistry
Renal function, fluoride formation and excretion were studied in seven patients during and after enflurane anaesthesia and surgery. The mean maximal plasma level of fluoride was 17.4 pM. It was reached 2 h after termination of anaesthesia. Pre‐operatively, fractional fluoride clearance (CF/CIn) was 0.31. During anaesthesia and surgery it decreased to 0.10 and postoperatively rose to 0.55 and 0.77 during two consecutive measurement periods. There was a highly significant correlation (P<0.001) between this increase in CF/CIn and the simultaneous rise in urinary pH between the two periods (r=0.91).