Premium
Effects of Enflurane and Halothane on the Microcirculation
Author(s) -
Novelli G. P.
Publication year - 1979
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1979.tb05476.x
Subject(s) - enflurane , halothane , medicine , microcirculation , norepinephrine , anesthesia , blood flow , ischemia , dopamine
Experiments have been carried out on the microvessels of the inesocaccurn of Wistar rats exposed to equipment doses of either halothane or enflurane. Parameters for evaluating microcirculation included venular flow, capillary How, vasomotricity of prccapillary sphincters and response to norepinephrine. Vennlar and capillary flow underwent relatively small modifications in both groups, but sensitivity to norepinephrine was increased in the halothane‐treated rats and decreased in the enflurane‐treated group. Although these variations were of a limited degree, the reduced sensitivity to norepinephrine in the enflurane group may express a certain degree of protection against tissue ischemia.