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Influence of Enflurane on Cerebral Blood Flow in Man
Author(s) -
Rolly G.,
Aken J. Van
Publication year - 1979
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1979.tb05475.x
Subject(s) - medicine , enflurane , cerebral blood flow , anesthesia , cerebrovascular circulation , halothane
Cerebral blood flow was measured by means of a 10‐channel cerebrograph in anesthe‐tised patients before and during 2% enfluranc. This investigation was carried out after carotid angiography; 2 3 mCi Xe 133 was injected into the internal carotid artery. The clearance curves of Xe l33 were captured by 10 scintillation counters. In addition to regional cerebral blood flow (rCBF), arterial blood pressure, heart rate, stroke volume, cardiac output and arterial blood gases were measured in seven adult patients. During 2% enflurane, a small, and in two regions a significant decrease in rCBF was observed. Mean arterial pressure and heart rate decreased significantly, but cardiac output did not. The decrease in PaCo2 was not significant.