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Cardiovascular Effects of Neurolept Anaesthesia in Patients with Coronary Artery Disease
Author(s) -
Tydén H.,
Westerholm C. J.
Publication year - 1979
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1979.tb01476.x
Subject(s) - medicine , pulmonary wedge pressure , anesthesia , pancuronium bromide , diazepam , blood pressure , cardiology , coronary artery disease , ventilation (architecture) , heart rate , cardiac output , mechanical engineering , engineering
An anaesthetic technique comprising a combination of phenoperidine (0.1 mg kg‐ l ), diazepam (0.06 mg kg ‐ l ) and pancuronium bromide (0.1 mg kg‐ 1 ) with controlled ventilation was evaluated in 12 patients with severe coronary artery disease. The heart rate, cardiac output and mean arterial blood pressure did not change significantly between the preinduction and postinduction measurements. The right atrial pressure and pulmonary capillary wedge pressure decreased significantly by 33% and 36%, respectively, probably due to the influence of positive‐pressure ventilation. There was no depression of the left ventricular performance.