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The Circulatory Response to Specific Ventilatory Patterns Using a Tidal Volume Ventilator
Author(s) -
Lindahl S.,
Kugelberg J.,
Okmian L.
Publication year - 1979
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1979.tb01464.x
Subject(s) - medicine , tidal volume , circulatory system , volume (thermodynamics) , intensive care medicine , cardiology , anesthesia , respiratory system , physics , quantum mechanics
The circulatory response to different ventilatory patterns during artificial ventilation was examined in 17 sternotomized piglets. A constant CO 2 ‐tension level was maintained in all investigations by reference to analyses of the end‐tidal infra‐red CO 2 fraction and arterial CO 2 ‐tension. The greatest variation in mean values for end‐tidal CO 2 ‐tension was 0.2 kPa. Total compliance and lung compliance were lower at a ventilator volume/pressure quotient of 20 compared to those at 80 ml/ kPa, and at f = 30 compared to f = 11 cycles/min. Higher cardiac output, lower pulmonary vascular resistance and systemic vascular resistance were measured at f = 11 (inspiration 20%) than at f = 30 (inspiration 50%). An increase in inspiration time by about 100% at the lower ventilatory frequency (f = 11) resulted in an increased work load for the right heart, reflected by a small decrease in cardiac output (7%). Changes in the duration of inspiration by about 100% at the higher ventilatory frequency (f = 30) resulted in a significant but uncompensated decrease in cardiac output and stroke volume. These results demonstrate the value of a rapid insufflation in order to give longer expiration time per minute for the benefit of the venous return and cardiac output.