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Cerebral Circulatory and Metabolic Stimulation with Nitrous Oxide in the Dog Reconfirmation by the Simultaneous Measurement of Ckrebral Blood Flow using Direct and Kety‐Schmidt Methods
Author(s) -
Oshita S.,
Ishikawa T.,
Tokutsu Y.,
Takeshita H.
Publication year - 1979
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1979.tb01438.x
Subject(s) - nitrous oxide , cerebral blood flow , medicine , circulatory system , anesthesia , blood flow , hemodynamics , stimulation , cardiology
In both the presencc and the absence of nitrous oxide (57%, end‐tidal), cerebral blood flow (CBF) was measured by a direct method in dogs, and compared to an indirect method (Kety‐Schmidt method), using argon as the tracer. Eighteen comparisons were made in five dogs at flows ranging from 45 to 123 ml per 100 g per minute. There was no systematic difference in CBF between the direct and indirect mcthods, and the ratio of direct CBF to indirect CBF was 1.03. The cerebral circulatory and metabolic stimulation effect of N 2 O in the dog was reconfirmrd.