Premium
*Cardiovascular Research Institute and Department of Anesthesia, University of California School of Medicine, San Francisco, CA 94143
Author(s) -
Severinghaus J. W.,
Stafford M.,
Bradley A. F.
Publication year - 1978
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1978.tb01405.x
Subject(s) - electrode , medicine , electrolyte , pco2 , glass electrode , anesthesia , reference electrode , chemistry
Transcutaneous P co2 electrodes have been constructed and evaluated on adults and children. Glass pH and silver reference electrodes were used at 44–45d̀C, with either circulating water and a copper jacket, or with internal electrical heating. The skin surface P co2 at 44d̀C is about 1.33 times Pa co2 plus 3 mmHg when measured with electrodes calibrated in gas at 44d̀C. Three temperature effects combine in this ratio: Heating raises blood Pco2 4.5%/d̀C, skin metabolism adds about 3 mmHg, and the cooling of the electrode active surface by skin increases electrode reading. Response time to step changes of Pa co2 was about 3 min to 63%, of which 1.2 min was sensor delay, the remainder skin C0 2 washout. It was found important to use ethylene glycol‐water mixtures rather than water for electrolyte to avoid bubble generation and drift. Heat transfer through the pH glass electrode has been increased by enlarging the internal silver electrode to virtually fill the entire glass electrode. Time required for initial vasodilation and stabilization is similar to that of tcP o2 electrodes, and accuracy of determination of Pa co2 appears to be better than ± 2 mmHg.