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Theoretical Considerations on the Potential Hazards of Hyperventilation During Anaesthesia
Author(s) -
Sørensen S. C.
Publication year - 1978
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1978.tb01383.x
Subject(s) - hyperventilation , medicine , anesthesia , oxygenation , ventilation (architecture) , general anaesthesia , engineering , mechanical engineering
The purpose of this paper is to evaluate the effect of hyperventilation on cerebral oxygenation. The best estimate of cerebral oxygenation is cerebral venous Po 2 (Pvo 2 ). Po 2 has been considered in relation to Paco 2 , during normoxaemia. In order to compare the effects of hyperventilation with the effects of hypoxaemia, Pvo 2 has also been considered in relation to Pao 2 , when Paco 2 is constant. Thc results indicate that the low Paco 2 values which may be seen in the operating room with manual ventilation have the same effect on cerebral oxygenation as severe hypoxaemia. It is emphasized that the brain is better protected against threats to cerebral oxygenation, e.g. hypotension, if Pao 2 , is kept close to normal during anaesthesia. During neurosurgical anaesthesia the advantages of excessive hyperventilation must be weighed against the threat it poses to oxygenation in healthy areas of the brain.