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CLINICAL STUDY OF PANCURONIUM BROMIDE AS A NEUROMUSCULAR BLOCKING AGENT IN ANAESTHESIA
Author(s) -
Telivuo Leo,
Ertama Pertti,
AaltoSetälä Matti,
Appelqvist Raimo,
Kaljunen Aate,
Karhunen Ulla,
Nuuttila Kaarlo,
Welling Ilmo
Publication year - 1971
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1971.tb00770.x
Subject(s) - pancuronium bromide , medicine , neuromuscular blocking agents , anesthesia , blockade , blocking (statistics) , neuromuscular monitoring , vecuronium bromide , neuromuscular blockade , receptor , statistics , mathematics
SUMMARY Pancuronium bromide has proved to be a useful non‐depolarizing long‐acting neuromuscular blocking agent which is nearly three times (2.42) as potent as alcuronium chloride. Pancuronium bromide blockade can be reversed fairly quickly by anticholinesterase agents, and die patient recovers to the 90% level of muscle tone in 15‐20 minutes. ZUSAMMENFASSUNG Pancuroniumbromid hat sich als brauchbarer nicht‐depolarisierender langwirkender neuromuskulärer Blocker erwiesen, der fast dreimal so stark (2,42) ist als Alcuroniumchlorid. Die Blockade durch Pancuroniumbromid kann mittels Anticholinesterasen ziemlich rasch aufgehoben werden; der Patient erreicht innerhalb von 15 bis 20 Minuten wieder 90% seines Muskeltonus.