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Clinical Experience With Citanest®, a New Local Anesthetic
Author(s) -
Sadove Max S.
Publication year - 1965
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1965.tb00549.x
Subject(s) - medicine , methemoglobinemia , drug , intensive care medicine , anesthesia , anesthetic , local anesthetic , therapeutic index , complication , surgery , pharmacology
SUMMARY Citanest represents an agent which definitely justifies further study and clinical usage. It has as its primary characteristics, rapid onset, good spread, and adequate duration. At this time its greatest characteristic is our impression of a definitely wider therapeutic index as it concerns the ratio of the amount of drug that may be administered to the amount of drug that causes toxic reactions. Though methemoglobinemia may be a complication of its use in large doses, we feel that this is not a contra‐indication to the drug's use but rather a factor worthy of further study because it seems to be reversible and not significantly frequent in the usual clinical dosage range.