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Studies of the Metabolism of Citanest C 14
Author(s) -
Geddes Ian C.
Publication year - 1965
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/j.1399-6576.1965.tb00520.x
Subject(s) - medicine , metabolism , urine , decarboxylation , excretion , in vivo , kidney , biochemistry , pharmacology , biology , catalysis , microbiology and biotechnology
SUMMARY Citanest C 14 has been shown to be degraded by liver and kidney slices. In vivo experiments demonstrate that metabolites are excreted in the urine and decarboxylation with excretion of C 14 0 2 has been demonstrated in the rat. Further studies are needed to establish all the pathways for metabolism of Citanest.