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Bipolar affective disorder in a male with a deletion of Y chromosome – a case report
Author(s) -
Olajossy Marcin,
OlajossyHilkesberger Luiza,
TkaczukWłach Joanna
Publication year - 2005
Publication title -
bipolar disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.285
H-Index - 129
eISSN - 1399-5618
pISSN - 1398-5647
DOI - 10.1111/j.1399-5618.2005.00198.x
Subject(s) - bipolar disorder , genetics , chromosome , karyotype , linkage (software) , psychiatry , x chromosome , medicine , biology , gene , mood
We report on a 25‐year‐old male with bipolar disorder, dysmorphic features and a deletion of the long arm of Y chromosome. A potential association between sex chromosome abnormalities and a susceptibility to major psychiatric disorders has been documented. However there have been very few reports on the coincidence of Y chromosome aberrations with bipolar disorder. Cytogenetic studies have contributed to the identification of several disease genes. Karyotyping of patients with bipolar disorder in order to identify candidate regions for linkage studies has been recommended.