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Hashimoto's encephalopathy presenting with bipolar affective disorder
Author(s) -
Müssig Karsten,
Bartels Mathias,
Gallwitz Baptist,
Leube Dirk,
Häring HansUlrich,
Kircher Tilo
Publication year - 2005
Publication title -
bipolar disorders
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.285
H-Index - 129
eISSN - 1399-5618
pISSN - 1398-5647
DOI - 10.1111/j.1399-5618.2005.00196.x
Subject(s) - bipolar disorder , pathological , encephalopathy , prednisolone , thyroiditis , medicine , electroencephalography , psychology , magnetic resonance imaging , pediatrics , psychiatry , mood , radiology , thyroid
Objective: We report on a rare case of Hashimoto's encephalopathy associated with a bipolar affective disorder. Case report: A 32‐year‐old woman presented with a bipolar affective disorder and Hashimoto's thyroiditis. Neurological investigations (magnetic resonance imaging of the brain and cerebrospinal fluid) did not reveal any pathological findings except for a pathological electroencephalogram (EEG). Despite consequent antidepressant treatment, the patient remitted only in conjunction with normalization of the EEG after short‐term treatment with high doses of prednisolone. Conclusion: In treatment resistant courses of disorders, the thorough clinical and laboratory investigation of our patient revealed a very efficient treatment strategy. Cases of Hashimoto's encephalopathy associated with the occurrence of a manic episode and hence with bipolar disorder are rare; this is the first reported case. However, clinicians should be alert to this possibility.