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Feasibility of prolonged continuous glucose monitoring in toddlers with type 1 diabetes
Author(s) -
Tsalikian Eva,
Fox Larry,
Weinzimer Stuart,
Buckingham Bruce,
White Neil H,
Beck Roy,
Kollman Craig,
Xing Dongyuan,
Ruedy Katrina
Publication year - 2012
Publication title -
pediatric diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.678
H-Index - 75
eISSN - 1399-5448
pISSN - 1399-543X
DOI - 10.1111/j.1399-5448.2011.00837.x
Subject(s) - medicine , glycemic , type 1 diabetes , hypoglycemia , continuous glucose monitoring , blood glucose self monitoring , diabetes mellitus , insulin , pediatrics , hemoglobin , insulin pump , endocrinology
Objective To examine the feasibility of continuous glucose monitoring (CGM) use in very young children with type 1 diabetes (T1D). Research design and methods Twenty‐three children less than 4 yr of age with T1D were provided with a FreeStyle Navigator ® (n = 21) or a Paradigm ® (n = 2) CGM device. At baseline, mean age was 3.0 ± 0.8 yr, mean hemoglobin A1c (HbA1c) was 8.0 ± 0.8%, 10 were using an insulin pump and 13 were on multiple daily injections. CGM use was evaluated over a 6‐month period. Results Three children dropped out of the study before the end of 6 months. Among the 20 children who completed 6 months of follow‐up, CGM use in month 6 was ≥6 d/wk in 9 (45%), 4 ≤ 6 d/wk in 2 (10%), and <4 d/wk in 9 (45%). Skin reactions were minimal. Although there was no detectable change in mean HbA1c between baseline and 6 months (7.9 and 8.0%, respectively), there was a high degree of parental satisfaction with CGM as measured on the CGM satisfaction scale questionnaire. A high percentage of glucose values were in the hyperglycemic range, and biochemical hypoglycemia was infrequent. Conclusion More than 40% of very young children were able to safely use CGM on a near‐daily basis after 6 months. CGM demonstrated frequent hyperglycemic excursions, with a large variability in glucose readings. Although improvement in glycemic control was not detected in the group as a whole, parental satisfaction with CGM was high.